1. AN ANTIMICROBIAL AND PHYTOCHEMICAL STUDY OF LEAVES (A case study of Mangifera indica and Carica papaya)
ABSTRACT
Phytochemical and antimicrobial screening analysis of Mangifera indica and Carica papaya indicated the presence of alkaloid, saponin, flavonoid, steroid, tannin, phenol and glycoside. Extract of Mangifera indica and Carica papaya were investigated for their ant...
2. ANALYSIS OF SOME MINERAL CONTENTS OF COCONUT WATER
Background of the Study
The coconut (Cocos nucifera L.) is a tropical plant which belongs to the order Arecales and family Arecaceae. It is widely grown in about 90 tropical regions of the world (Peggy, 2007).Every part can be utilized roots, husk, leaves and fruit. The...
3. THE EFFECTS OF DIFFERENT PROCESSING TECHNIQUES ON THE ORGANOLEPTIC QUALITY OF SOY MILK
Background of the study
His of Soymilk: Soybeans belongs to the family leguminous, subfamily papiliondase and the genus Glycine Max. (Ricker and Morse, 1984), other normendatures which have been used include phaseolus Max, Soja Max Piper and Sojahispidemoech.
It...
4. ANTIBACTERIAL ACTIVITY OF THE LEAF EXTRACTS OF ALCHORNEA CORDIFOLIA (Euphorbiaceae) AGAINST ISOLATES FROM PATIENTS WITH RESPIRATORY TRACT INFECTION IN UNIVERSITY TEACHING HOSPITAL
ABTRACT
Many bacterial species have been reported to develop resistance to antibiotics commonly prescribed for respiratory tract infections. Therefore, the need to search for natural products for remedy of this problem cannot be overemphasized. One hundred and eighty (180) specimens wer...
5. ANALGESIC, ANTI-INFLAMMATORY AND OTHER PHARMACOLOGICAL ACTIVITIES OF METHANOL LEAF EXTRACT OF OLAX SUBSCORPIOIDEA OLIV (OLACACEAE) IN LABORATORY ANIMALS
ABSTRACT
Synthetic analgesic and anti-inflammatory drugs have major side effects such as constipation, nausea and vomiting, sedation and mental clouding, etc.,which have significantly limited their use.There is therefore, an intensification of search for newer analgesic and anti-inflamm...
6. ANTI-HYPERLIPIDEMIC POTENTIAL OF VITEX DONIANAETHANOLEXTRACTS ON POLOXAMER 407 INDUCED HYPERLIPIDEMIC AND NORMAL RATS
ABSTRACT
Anti-hyperlipidemic potential of extracts (aqueous, 70% methanol, 70% ethanol and 70%, acetone) of Vitexdoniana leaves, stem bark and root bark on poloxamer 407 induced hyperlipidemic and normal rats was investigated. Phytochemical screening of the extracts revealed the presenc...
7. COMPARATIVE EVALUATION OF THE HYPOTENSIVE EFFECTS OF THE SEED AND LEAF EXTRACTS OF MORINGA OLEIFERA LAM (Moringaceae) IN LABORATORY ANIMALS
ABSTRACT
Moringa oleifera is locally used in Nigeria for the management of respiratory disorders, hypertension and poor blood circulation among other ailments. However, all parts of the plant are blindly used because the exact part of this plant and / or extractive solvent that provides...
8. EVALUATION OF ANTITRYPANOSOMAL EFFECT OF STEM-BARK EXTRACTS OF SECURIDACA LONGEPEDUNCULATA (FRES. HOLL) AGAINST TRYPANOSOMA BRUCEI BRUCEI INFECTION IN WISTAR RATS
ABSTRACT
Due to numerous problems associated with current treatment of trypanosomosis, there is increasing need to find effective drug against trypanosomosis ravaging sub-Saharan Africa from traditional medicinal herbs. This work is aimed at evaluating efficacy of stem-bark extracts of...
9. FORMULATION STUDIES OF TABLETS CONTAINING ADANSONIA DIGITATA L. MUCILAGE AS MATRIX FORMER
ABSTRACT
The aim of this study was to investigate the ability of Adansonia digitata mucilage (ADM), a hydrophilic plant polymeric material to prolong the release of Metoprolol tartarate (MPT) from matrix tablet formulations compared with semi -synthetic polymer-HPMC60SH4000 matrices. Ph...
10. PHARMACOGNOSTIC AND ANTIBACTERIAL STUDIES OF THE LEAVES OF CHROMOLAENA ODORATA (L.) KING & ROBINSON (ASTERACEAE)
ABSTRACT
The plant, Chromolaena odorata (L.) King & Robinson is a member of the Asteraceae family. It grows abundantly in Southern Nigeria where its leaves are used as traditional herbal treatment for wounds and fevers. The plant, C. odorata was therefore investigated for antibacter...
11. PHARMACOGNOSTIC AND ANTICONVULSANT STUDIES ON GLOSSONEMA BOVEANUM DECNE (APOCYNACEAE)
ABSTRACT
Glossonema boveanum Decne is a hairy canescent perennial herb belonging to the Apocynaceae. Traditionally, the powdered whole plant is use for the treatment of many illnesses including epilepsy. This study is aimed at establishing some of the pharmacognostic features of the pow...
12. PHYTOCHEMICAL AND SOME PHARMACOLOGICAL STUDIES OF THE LEAF, STEM BARK AND ROOT BARK EXTRACTS OF STACHYTARPHETA ANGUSTIFOLIA (MILL) VAHL. (VERBENACEAE
ABSTRACT
The extracts of the leaf, stem bark and root bark of Stachytarpheta angustifolia (Mill) Vahl. (Verbenaceae), were subjected to preliminary phytochemical screening and the result revealed the presence of carbohydrates, steroids, cardiac glycosides, terpenoids, flavonoids, tannin...
13. PHYTOCHEMICAL AND ANTI-INFLAMMATORY STUDIES OF N-BUTANOL SOLUBLE FRACTION OF THE METHANOLIC EXTRACT OF THE AERIAL PARTS OF INDIGOFERA HIRSUTA LINN (LEGUMINOSAE)
Abstract
Indigofera hirsuta Linn. (Leguminosae) is a well-known plant used in African traditional medicine as an anti-inflammatory, antibacterial, antiulcer, anti-venom and anticonvulsant. The air-dried aerial parts of I. hirsuta was extracted with methanol using a soxhlet extractor and...
14. AN IN VITRO STUDY OF THE ANTIBACTERIAL PROPERTIES OF SELECTED PLANT SPECIES FOUND IN ADAMAWA STATE, NIGERIA
ABSTRACT
The antibacterial activity of plant extracts compared to a known antibiotic (ampicillin) was evaluated against ten gram-negative and gram-positive bacteria which can infect humans. In addition, the efficacies of different extraction methods were studied. Soxhlet, cold aqueous,...
15. PHYTOCHEMICAL INVESTIGATIONS AND ANTICANCER ACTIVITY STUDIES ON THE LEAVES OF FICUS SYCOMORUS LIN. (FAMILY: MORACEAE)
ABSTRACT
Ficus sycomorous (Family Moraceae) is a plant used in African traditional medicine to treat mental illness, dysentery, cough, diarrhea, tuberculosis and cancer. The aim of this research work is to isolate and characterize some compounds from the leaf of Ficus sycomorous and to...
16. PHYTOCHEMICAL, PHARMACOLOGICAL AND FORMULATION STUDIES OF Andrographis paniculata Nee Acanthacae
ABSTRACT
The leaves of Andrographis paniculata acanthaceae is used locally in Northern Nigerian for the treatment of hypertension without quantification or dosage standardization. This work was primarily set out to find justification for the local medicinal use of this plant and to scie...
17. STUDIES ON ANTIHAEMORRHAGIC AND ANTIBACTERIAL PROPERTIES OF BULB JUICE, ETHANOL AND AQUEOUS EXTRACTS OF ALLIUM SATIVUM LINN. (LILLIACEAE) AGAINST MENINGEAL BACTERIA
ABSTRACT
Bacterial meningitis (BM) is a devastating air-borne infectious disease of humans that causes cellular hemorrhagic sepsis, metabolic, neurologic and endocrine disorders and constitutes a serious threat to public health. Where malnutrition is linked to BM, it is a great economic...
18. THE COMPARATIVE EFFECTS OF AQUEOUS AND ETHANOL FRUIT EXTRACTS OF PHOENIX DACTYLIFERA ON THE HIPPOCAMPUS AND CEREBELLAR CORTEX OF ARTESUNATE-AMODIAQUINE TREATED ADULT WISTAR RATS
ABSTRACT
Amidst the current rise in the usage of artemisinin-based combination therapies as the first line treatment of falciparum resistant malaria in the Tropics, artesunate-amodiaquine combination therapy have been found to have degenerative and toxicity effects. This study was aimed...
19. TOXICOLOGICAL AND ANTI-HYPERGLYCAEMIC PROPERTIES OF AQUEOUS LEAF EXTRACT OF PERSEA AMERICANA MILL (LAURECEAE) IN NORMOGLYCAEMIC AND ALLOXAN-INDUCED HYPERGLYCAEMIC WISTAR RATS
ABSTRACT
Diabetes mellitus has become a global health burden leading to an increase in the search for herbal anti-hyperglycaemic agents as alternative to synthetic ones. Persea americana popularly known as avocado pear have been known for its nutritional and medicinal properties. The le...
20. EFFECT OF CAFFEINE ON PHARMACOKINETICS OF PARACETAMOL IN HEALTHY HUMAN VOLUNTEERS: A CASE STUDY OF PANADOL EXTRA®
ABSTRACT
Acetaminophen or paracetamol is an analgesic and anti-pyretic agent widely used for treatment of headaches, minor pains and in combination with other medications like cold remedies and opoid analgesics. Individuals with headaches and minor pains tend to use paracetamol with caf...
21. PHYTOCHEMICAL AND SOME BIOLOGICAL STUDIES OF THE METHANOL LEAF EXTRACT OF ASPILIA AFRICANA (PERS.) C. D. ADAMS (ASTERACEAE)
Abstract
Aspilia africana, (Pers) C.D. Adams; (Asteraceae), a semi perennial woody plant, commonly known as haemorrhage plant is widely distributed across tropical Africa and all parts of Nigeria. The plant is well known in folkloric medicine for its anti-haemorrhagic uses and for the t...
22. PHARMACOGNOSTIC, ANTIOXIDANT AND ANTIMICROBIAL STUDIES OF THE LEAVES OF AMARANTHUS VIRIDIS LINN.(AMARANTHACEAE)
ABSTRACT
Amaranthus viridis (Amaranthaceae), an annual herb, used in traditional medicine as diuretic and emollient, in poultices on inflammations, boils or abscesses, as well as in the treatment of gonorrhea, piles, fever, filaria, dysentery etc. This study focussed on the evaluation o...
23. PHYTOCHEMICAL AND ANTIVENOM EVALUATIONS OF METHANOL LEAF EXTRACT OF CLERODENDRUM CAPITATUM (WILLD) SCHUM. AND THONN. (VERBENACEAE)
ABSTRACT
Clerodendrum capitatum (Willd) Schumach and Thonn. is a common medicinal plant found mainly in the tropical and sub-tropical regions of the world where it is used in traditional medicine for the treatment of various conditions including erectile dysfunction, wounds, diabetes me...
24. SOME CARDIOVASCULAR ACTIVITIES OF THE AQUEOUS LEAF EXTRACT OF CROTON ZAMBESICUS LINN (EUPHORBIACEAE) IN LABORATORY ANIMALS
Abstract
Croton zambesicus Linn (Euphorbiaceae) is a highly valued medicinal plant in Nigeria and West African sub-region. It is used by traditional medicine practitioners in the treatment of various ailments including hypertension. This study aims to determine some cardiovascular activ...
25. SOME NEUROPHARMACOLOGICAL STUDIES ON ETHANOL EXTRACT AND FRACTIONS OF TAPINANTHUS GLOBIFERUS A. RICH MISTLETOE ON VITELLARIA PARADOXA HOST IN LABORATORY ANIMALS
ABSTRACT
Tapinanthus globiferus is a semi-parasite mistletoe which grows on branches of large number of trees including Vitellaria paradoxa. It used locally in the management of insomnia, epilepsy, anxiety, headaches and hypertension. This study evaluated the toxicity and neuropharmacol...
26. SOME UTEROTONIC PROPERTIES OF AQUEOUS LEAF EXTRACT OF SIDA CORYMBOSA (Fries) IN LABORATORY ANIMALS
ABSTRACT
Uterotonic property is the characteristic innate ability of a substance to spontaneously initiate and maintain uterine contractions due to its chemical composition. Over centuries, sub-saharan Africans have been using Sida corymbosa leaf extract during labour with the claims th...
27. EFFECT OF AQUEOUS ETHANOL LEAF EXTRACT OF COMBRETUM MICRANTHUM G. DON (COMBRETACEAE) ON SOME INDUCED SYSTEMIC INFLAMMATORY IMMUNE RESPONSE SYNDROMES IN MICE AND RATS
Abstract
The cellular immunity is often suppressed by infection, disease conditions and drug medication that are in continous association with mankind. Combretum micranthum is a plant known for its antioxidant, antimicrobial, anti-inflammatory and various other properties of immune boos...
28. EFFECT OF GREEN TEA (CAMELLIA SINENSIS) ON THE PHARMACOKINETIC PROFILE OF CEPHALEXIN IN HEALTHY HUMAN VOLUNTEERS
ABSTRACT
Tea is a herb commonly consumed globally. Herbs are often taken concurrently with conventional medicines which results in increased potential of drug-herb interactions, and this may have important clinical significance based on an increasing number of reports of such interactio...
29. EVALUATION OF THE DISSOLUTION AND OTHER CHARACTERISTICS OF CYCLODEXTRIN MOLECULAR INCLUSION COMPLEXES OF ARTEMETHER
ABSTRACT
The present study aimed to improve the dissolution rate, solubility and ultimately, bioavailability of poorly soluble artemether, an antimalarial drug, through inclusion complex formation with hydroxypropyl-β-cyclodextrin. The solid complexes of artemether and hydroxypropy...
30. PHARMACOGNOSTIC AND ANTI INFLAMMATORY STUDIES OF THE STEM BARK OF FICUS GLUMOSA DEL. (MORACEAE)
ABSTRACT
Ficus glumosa is widely distributed in Northern part of Nigeria; it has been exploited for both its medicinal and economic importance. It is traditionally used for the treatment of number of ailments including gastrointestinal, respiratory, inflammatory, cardiovascular disorder...
31. PHARMACOGNOSTIC AND ANTI-INFLAMMATORY STUDIES ON THE LEAF OF LUDWIGIA ABYSSINICA RICH. (ONAGRACEAE)
ABSTRACT
Ludwigia abyssinica Rich (Onagraceae) is a plant native to South America but now widely distributed in Africa. It has been exploited for its medicinal and economic importance. It is traditionally used for the treatment of a number of ailments such as cough, skin diseases, sores...
32. PHARMACOGNOSTIC AND ANTIOXIDANT STUDIES OF THE PSEUDOBULBS OF EULOPHIA GUINEENSIS LINDL (ORCHIDACEAE)
ABSTRACT
Eulophia species are cultivated worldwide; it is one of the largest orchid‘s genera in Africa. They are believed to cure many diseases. Eulophia guineensis Lindl (Orchidaceae) is a multipurpose plant, native to West Africa. Traditionally, it is exploited in the treatment...
33. SUSCEPTIBILITY PROFILES OF SOME BACTERIA ISOLATED FROM STOOL OF DIARRHOEAL PATIENTS TO THE STEM AND ROOT BARKS EXTRACTS OF FICUS SYCOMORUS Linn (Moracae)
ABSTRACT
Effective antibiotic management of diarrhoea caused by bacterial organisms faces challenge of antibiotic resistance which combines to pose serious problems. Local people often use some plants to treat diarrhoea. The efficacy of one of such plant is the subject of this investiga...
34. DANIELLIA PHARMACOGNOSTIC AND BIOLOGICAL STUDIES OF THE ROOT OF OLIVERI (ROLFE) HUTCH. & DALZ. (CAESALPINIACEAE)
ABSTRACT
Daniellia oliveri is one of the most extensively utilized medicinal plants; it is a tree all of whose parts are used in Nigeria and some West African countries for the treatment of various ailments example the root is used as chewing stick. In the bid to standardize this plant,...
35. EVALUATION OF AQUEOUS AND METHANOL ROOT EXTRACTS OF CALOTROPIS PROCERA AIT (ASCLEPIADACEAE) FOR ANTI-ASTHMATIC ACTIVITY ON WISTAR RATS AND GUINEA PIG ILEUM
ABSTRACT
Asthma, which affects an estimated 300 million people worldwide, is an incurable health disorder of a major public health concern globally. The present orthodox therapy for asthma has several drawbacks including many undesirable side effects and high cost of management (especia...
36. PHARMACOLOGICAL RATIONALE FOR THE USE OF SOME MEDICINAL PLANTS AS ANTIEPILEPTIC AGENTS IN NIGERIA
ABSTRACT
The effects of the hydro-alcoholic root bark extracts of C. edulis and B. aegyptiaca were studied on pentylenetetrazole (PTZ) and Maximal electroshock (MES)-induced seizures in animal models. The effects of Flumazenil and Naloxone were studied on the anticonvulsant activity of...
37. PHYTOCHEMICAL AND ANTI BACTERIAL STUDIES ON THE STEM BARK OF LANNEA BARTERI. (OLIV.) ENGL. (ANACARDIACEAE)
ABSTRACT
Lannea bartei (Oliv.) Engl. is a plant with medicinal and commercial uses found usually in the tropical regions like Africa especially Ivory Coast. The plant is used traditionally to treat various diseases including wound healing and as anti diarrhoea. This research is aimed at...
38. PHYTOCHEMICAL AND BIOLOGICAL STUDIES ON THE SEEDS OF JATROPHA CURCAS LINN. (EUPHORBIACEAE)
ABSTRACT
Jatropha curcas Linn. (Euphorbiaceae) is a shrub that grows up to 5m in height. It thrives well in tropical countries. It grows in the wild as an uncultivated, non-food plant. It is traditionally used as a living fence to protect gardens from animals. An ethnobotanical survey o...
39. ANTIBACTERIAL ACTIVITIES OF CRUDE Curcuma longa EXTRACT MEDIATED SILVER NANO PARTICLES AGAINST ISOLATES FROM DIABETIC PATIENTS WITH FOOT INFECTIONS
ABSTRACT Curcuma longa are traditionally used for the treatment of ulcers, hepatic disorder, wound healing and boost glucose control. This study assessed the phytochemical compositions (quantitative and qualitative), antibacterial activities of C. longa crude extracts, synthesis and characterisat...
40. EVALUATION OF MOLLUSCICIDAL ACTIVITIES OF CRUDE AND ALKALOIDAL FRACTION OF ANOGEISSUS LEIOCARPUS (AFRICAN BITCH) AND PSEUDOCEDRELA KOTSCHYI (DRY ZONE CEDAR) ON VECTOR OF SCHISTOSOMIASIS
ABSTRACT
Over the years, the use of plant-based molluscicides has received substantial consideration in the satisfaction for cost-effective alternatives to chemotherapy and synthetic molluscicides in schistosomiasis control. This study was aimed at evaluating the molluscicidal potential...
41. SUSCEPTIBILITIES OF Salmonella typhi AND OTHER BACTERIAL PATHOGENS TO ANTIBIOTICS AND HOT AQUEOUS EXTRACT OF Hibiscus sabdariffa
ABSTRACT
The susceptibilities of Salmonella typhi and other pathogens to antibiotics and hot aqueous extract of Hibiscus sabdariffa were investigated using agar diffusion and agar well diffusion methods respectively. Salmonella typhi was sensitive to ampicillin, cetriaxone, ciprofloxaci...
42. OPTIMIZATION STUDIES OF PROCESS PARAMETERS FOR THE ADSORPTION OF COPPER AND ARSENIC IONS FROM SIMULATED WASTE WATER USING CHITOSAN AND CHITOSAN – ZEOLITE BEADS
ABSTRACT
This research presents the “Optimization Studies of Process Parameters for the Adsorption of Copper and Arsenic Ions from Simulated Waste Water using Chitosan and Chitosan – Zeolite Beads” which was achieved by developing adsorbents of chitosan and chitosan &n...
43. EVALUATION OF SOME NATURAL AND SYNTHETIC PRODUCTS AGAINST AFRICAN TRYPANOSOMIASIS
ABSTRACT
The chemotherapy of African trypanosomiasis, a fatal protozoal disease of man and animals is beset with many problems including a limited repertoire of expensive compounds, drug toxicity and resistance and protracted treatment protocols. In order to improve chemotherapy, some n...
44. STUDIES ON THE ANTIVENOM ACTIVITIES OF THE AQUEOUS EXTRACTS OF PAULLINIA PINNATA AND DETARIUM MICROCARPUM AGAINST ECHIS CARINATUS (CARPET VIPER) VENOM
ABSTRACT
In rural savannah areas of Nigeria, Echics ocellatus (Carpet viper) is responsible for high incidence of snakebite morbidity and mortality. The snakebites are commonly treated with plant extracts in form of traditional medicine. The antivenom activity of Paullinia pinnata Linn...
45. SOLAR PHOTOCATALYTIC DEGRADATION OF ORGANIC POLLUTANTS IN LOCAL DYEING WASTEWATER USING NEEMMODIFIED GRAPHITIC CARBON NITRIDE (g-C3N4)
ABSTRACT
The discharge of dyeing wastewater containing high concentration of contaminants from the local dyeing industry has caused a serious environmental concern. The present study reports the synthesis of graphitic carbon nitride and itsutilization in degradation of dyeing effluent p...
46. ANTIPLASMODIAL ACTIVITY OF AQUEOUS AND ETHANOLIC EXTRACTS OF ANACARDIUM OCCIDENTALE AND CYMBOPOGON CITRATUS
ABSTRACT
The search for antimalarial compounds was necessitated by Plasmodium falciparum resistance to most antimalarial drugs. In endemic countries where malaria is prevalent, medicinal plants are often used to treat malaria. In this study, the in vitro antimalarial activities of crude...
47. KINETICS AND OPTIMIZATION OF PHENOL UPTAKE FROM AQUEOUS SOLUTION USING AGRICULTURAL WASTES
ABSTRACT The uptake of phenol from simulated aqueous solution using agricultural wastes as adsorbents is the focus of this research work. The agricultural wastes used were corn cob and rice husk which were modified with tetraoxophosphate V acid (H3PO4) and carbonized to give corn cob activated ca...
48. MODIFICATION OF STAINLESS STEEL SURFACES FOR ADVANCED FUNCTIONALITIES
SUMMARY
In industry, business, and homes worldwide, metal alloys called stainless steels are used extensively. Stainless steel is a generic term for a large family of iron-based alloys containing a minimum of 10.5% chromium content by weight. The primary alloying element, chromium, form...
49. STATISTICAL MODELING AND OPTIMIZATION OF CARBON SEQUESTRATION BY ABSORPTION USING AQUEOUS AMMONIA
Statement of the Problem
The aggressive exploitation of fossil fuels and other natural resources has contaminated the air we breathe, the water we drink, and the land we inhabit. Over a million tons of carbon (iv) oxide 3 and other climatically-important “greenhouse” gases h...
50. ACETYLATION OF CORN COB AND MANGO KERNEL- KINETICS AND APPLICATION FOR NON-AQUEOUS ADSORPTION PROCESSES
Justification for the Research
Residents of wetlands like the Nigeria’s Niger delta are concerned about the environmental impact of residual oil spill into receiving surface waters and land. The adverse effect of oil spill to the ecosystem and the long term effect of environmental...
