1. FEVER AS A PREDICTOR FOR MALARIA INFECTION AMONG INDIVIDUALS ATTENDING KOFAI PHCC IN ARDO-KOLA LGA TARABA STATE
BACKGROUND OF STUDY
Malaria is a life threatening parasitic disease transmitted by female Anopheles mosquitoes. In Nigeria, malaria is responsible for around 60% of the out-patient visits to health facilities, 30% of childhood death, 25% of death in children under one y...
2. COMMUNITY-BASED DIAGNOSIS AND MANAGEMENT OF CHILDHOOD MALARIA USING RAPID DIAGNOSTIC TEST AND MANAGEMENT WITH ARTEMISININ –BASED COMBINATION THERAPY IN TARABA STATE-NIGERIA
ABSTRACT
A cross-sectional study was conducted for fifteen (15) months (May, 2012 to July, 2013) to assess the efficacy of Rapid Diagnostic Test (RDT) in&n...
3. ANTIMALARIAL SUSCEPTIBILITY AND DRUG RESISTANCE CHARACTERIZATION STUDIES OF PLASMODIUM SPECIES ISOLATES FROM PATIENTS IN NIGERIA
ABSTRACT
About half of Nigerian population experience at least one episode of malaria per year, resulting in high morbidity and mortality and loss of economic value. Retrospective study of the profile of malarial patients and the antimalarial drugs prescribed at Umaru Musa Yaradua memor...
4. EFFECT OF CHRONOMODULATED ARTESUNATE ON RENAL AND HAEMATOLOGICAL TOXICITY IN CISPLATIN-TREATED WISTAR RATS
ABSTRACT
Cisplatin is a non-cell-cycle dependent chemotherapeutic agent used in the treatment of several common solid tumours. However, an array of serious toxicities in various organs and systems limit its therapeutic use. Artesunate, a semisynthetic derivative of artemisinin is the re...
5. SURFACE ACTIVITY AND RELEASE PROPERTIES OF SOME TROPICAL GUMS IN ARTEMETHER AND ARTESUNATE SODIUM TABLET FORMULATIONS
ABSTRACT
Plant gums are natural polymers with low toxicity, high biodegradability and high compatibility with drugs making them useful as pharmaceutical excipients in solid, semi-solid and liquid formulations. This work was aimed at evaluating the surface activity and release properties...
6. THE COMPARATIVE EFFECTS OF AQUEOUS AND ETHANOL FRUIT EXTRACTS OF PHOENIX DACTYLIFERA ON THE HIPPOCAMPUS AND CEREBELLAR CORTEX OF ARTESUNATE-AMODIAQUINE TREATED ADULT WISTAR RATS
ABSTRACT
Amidst the current rise in the usage of artemisinin-based combination therapies as the first line treatment of falciparum resistant malaria in the Tropics, artesunate-amodiaquine combination therapy have been found to have degenerative and toxicity effects. This study was aimed...
7. IN VITROANTIMALARIAL SUSCEPTIBILITY OF PLASMODIUM FALCIPARUM ISOLATES FROM PATIENTS ATTENDING A HEALTH FACILITY IN NIGERIA
ABSTRACT
The continous emergence and spread of resistant strains of Plasmodium falciparumisolates to single and combined antimalarial drug has resulted to increase in mortality rate associated with the disease, especially in the African Continent as a whole and Nigeria in particular whe...
8. THE EFFECT OF QUININE-ARTESUNATE CO-ADMINISTRATION ON SOME BIOCHEMICAL PARAMETERS IN PLASMODIUM BERGHEI PARASITIZED SWISS ALBINO MICE AND RATS
ABSTRACT
Malaria has been the leading cause of morbidity and mortality in most Sub-saharan Africa and Southeastern Asia. Combination therapy has been recommended for treatment of malaria and this could lead to drug-drug interaction. This work titled “The effect of Quinine-Artesuna...
