1. COMPARATIVE RELATIVE BIOAVAILABILITY STUDIES OF SIX BRANDS OF OFLOXACIN MARKETED
ABSTRACT
This study was aimed at assessing the comparative bioavailability of six brands of ofloxacin marketed in Zaria. Comparative bioavailability studies of six brands of ofloxacin marketed in Zaria was successfully conducted. Quality assessment was conducted on the randomly selected...
2. COMPARATIVE IN-VITRO BIOEQUIVALENCE STUDIES OF DIFFERENT SAMPLES OF TINIDAZOLE TABLETS
ABSTRACT
Health care professionals are faced with a large number of multisource products from which therapeutically equivalent products are being selected for various reasons. Consequently, an increased availability and use of generic products has been seen during the last four decades....
3. COMPARATIVE BIOAVAILABILITY STUDIES OF PARACETAMOL BRANDS IN HUMANS
ABSTRACT
The comparative bioavailabilities (bioequivalence) of five generic brands of paracetamol were compared in six (6) healthy male volunteers. The aim was to study whether the generic brands are bioequivalent to the standard brand. The study was carried out following oral administr...
4. EVALUATION OF THE DISSOLUTION AND OTHER CHARACTERISTICS OF CYCLODEXTRIN MOLECULAR INCLUSION COMPLEXES OF ARTEMETHER
ABSTRACT
The present study aimed to improve the dissolution rate, solubility and ultimately, bioavailability of poorly soluble artemether, an antimalarial drug, through inclusion complex formation with hydroxypropyl-β-cyclodextrin. The solid complexes of artemether and hydroxypropy...
5. EFFECTS OF CHLORPHENIRAMINE ON THE PHARMACOKINETICS OF ASCORBIC ACID IN HEALTHY MALE VOLUNTEERS
ABSTRACT
Ascorbic acid is a vitamin commonly used in the treatment of common cold and scurvy. It interacts with some drugs during absorption from the gastrointestinal tract, in the systemic circulation or during metabolism in the liver. However, interaction between ascorbic acid and chl...
