1. A STUDY ON GARLIC (Allium sativum L.) MEAL AND ITS EFFECT AS A FEEDING INGREDIENT IN BROILER CHICKEN DIET
BACKGROUND OF THE STUDY
Because of the alleged harmful consequences of antibiotic resistance on human health, there is growing demand to decrease or abolish the use of antibiotics in poultry feed (Javandel et al., 2008). A nationwide regulation prohibit...
2. EFFECT OF VITAMINS C AND E ON MEMORY IN ADULT MICE
Vitamin C, also known as L-ascorbic acid, is a water-soluble vitamin that is naturally present in some foods, added to others, and available as a dietary supplement and is destroyed by heat or reduced by prolonged storage (Weinstein et al., 2001). Humans, unlike most...
3. EVALUATION OF ANTIOXIDANT POTENTIAL OF MONODORA MYRISTICA (AFRICAN NUTMEG)
BACKGROUND OF THE STUDY
Lipid oxidation is one of the major reasons that food deteriorate and is caused by the reaction of fat and oil with molecular oxygen, leading to off-flavours that are generally called rancidity(Basturk et al., 2...
4. THE ECONOMIC IMPORTANCE OF FERMENTATION
Background of the Study
Since fruit ferments naturally, fermentation precedes human history. However, human began to take control of fermentation process art some points in time. There is strongest evidence that people were fermenting beverage.
...5. A COMPARATIVE REVIEW ON MICRO-ORGANISM ASSOCIATED WITH THE SPOILAGE OF BANANA
Bacteria do not seem important in the initial spoilage of whole fruits like banana instead such spoilage often is initiated by molds. These organisms have enzymes that contribute to the weakening and penetration of the protective outer skin. Many microorganisms have been isolate...
6. AN ANTIMICROBIAL ANALYSIS AND PHYTOCHEMICAL OF Mangifera indica AND Carica papaya LEAVES
BACKGORUND TO THE STUDY
It is well known that in order for a plant to protect itself, it creates certain compounds that can also protect humans from sickness. Today, there are approximately 4000 distinct phytochemicals that have the potential to alter disorders such as...
7. AN ASSESSMENT INTO THE FREQUENCY OF URINARY TRACT PARASITES IN PATIENTS
Background to the Study
An infection of any region of the urinary system is referred to as a urinary tract infection (often abbreviated as UTI). The kidneys, ureters, bladder, and urethra are the components that make up the urinary tract. Any component...
8. AN INVESTIGATION OF CHARACTERIZATION AND ISOLATION OF FUNGI ASSOCIATED WITH “SPOILED” TOMATOES IN GWAGWALADA
INTRODUCTION
Vegetables are an essential food product that are both economically important and nutritionally significant. Vegetables naturally play an important part in human nutrition by delivering the required growth factors in the form of vitamins and key minerals in...
9. AN INVESTIGATION ON THE COMMONESS OF URINARY TRACT PARASITES AMONG PATIENTS
Background to the Study
An infection of any region of the urinary system is referred to as a urinary tract infection (often abbreviated as UTI). The kidneys, ureters, bladder, and urethra are the components that make up the urinary tract. Any component...
10. ASSESSMENT ON THE ROLE OF PLANTS IN THE TREATMENT OF DISEASES CAUSED BY MICRO-ORGANISMS BASED IN THE NATURAL PRODUCTS
BACKGROUNG OF STUDY
Infectious diseases are a significant cause of morbidity and mortality worldwide, accounting for approximately 50% of all deaths in tropical countries and as much as 20% of deaths in the Americas. Despite the significant progress made in microb...
11. ANALYSIS OF SOME MINERAL CONTENTS OF COCONUT WATER
Background of the Study
The coconut (Cocos nucifera L.) is a tropical plant which belongs to the order Arecales and family Arecaceae. It is widely grown in about 90 tropical regions of the world (Peggy, 2007).Every part can be utilized roots, husk, leaves and fruit. The...
12. AN EVALUATION OF THE APHRODISIAC AND FERTILITY ENHANCING EFFECT OF THE METHANOLIC ROOT EXTRACT OF CISSUS POPULNEA Guill.And Perr. (Vitaceae)
ABSTRACT
Aphrodisiac activity of Cissus populnea was assessed using physical, biochemical and psychological methods. Rats were randomized into five groups of six rats. The first group received normal saline (10ml/kg), the second, third and fourth groups received extract doses of 250mg/k...
13. ANALGESIC, ANTI-INFLAMMATORY AND TOXICITY STUDIES ON METHANOLIC LEAF EXTRACT OF ROTHMANNIA LONGIFLORA SALISB (RUBIACEAE) IN RATS AND MICE
ABSTRACT
The herbalists in several African Countries have used Rothmannia longiflora decoctions as febrifugal and analgesic agent. The present study examined the analgesic, anti-inflammatory and toxicological profile of the methanolic extract of the plant in experimental animals. The pr...
14. ANTIBIOTICS SUSCEPTIBILITY AND MOLECULAR CHARACTERIZATION OF CLINICAL ISOLATES OF E. coli FROM UNIVERSITY TEACHING HOSPITAL IN NIGERIA
ABSTRACT
Antimicrobial drug resistance is a global challenge with the emergence of resistant bacterial strains worldwide. This study was conducted to determine the incidence of E. coli in ABUTH Shika, Zaria (from March 2011 to February 2012), their antibiotics susceptibility pattern, mo...
15. DESIGN, SYNTHESIS, ANTIMALARIAL EVALUATION AND COMPUTATIONAL STUDIES OF SOME CHALCONE DERIVATIVES
ABSTRACT
Inspired by the previous findings on the structural requirements needed for good antimalarial activity by chalcones against Plasmodium proteases, seventeen chalcone derivatives were designed and synthesized using Claisen-Schmidt condensation of appropriate aldehydes and methyl...
16. ANTIHYPERGLYCAEMIC AND ANTIBACTERIAL EVALUATION OF METHANOL TUBER EXTRACT OF CHLOROPHYTUM ALISMIFOLIUM BAKER (LILIACEAE)
ABSTRACT
Diabetes mellitus is a metabolic disorder which affects about 346 million people globally. Synthetic antidiabetic agents are expensive and also associated with side effects. In a bid to develop cheaper and safer antidiabetic agents, this study was carried out to determine the e...
17. ANTI-HYPERLIPIDEMIC POTENTIAL OF VITEX DONIANAETHANOLEXTRACTS ON POLOXAMER 407 INDUCED HYPERLIPIDEMIC AND NORMAL RATS
ABSTRACT
Anti-hyperlipidemic potential of extracts (aqueous, 70% methanol, 70% ethanol and 70%, acetone) of Vitexdoniana leaves, stem bark and root bark on poloxamer 407 induced hyperlipidemic and normal rats was investigated. Phytochemical screening of the extracts revealed the presenc...
18. ANXIOLYTIC PROPERTIES OF MITRACARPUS VILLOSUS (SW) DC.LEAF EXTRACTS IN MICE AND RATS
ABSTRACT
The leaf of Mitracarpusvillosus (Sw.) DC. (Rubiaceae) is used in West African folk medicine for the management of a plethora of stress-related diseases including headaches and toothaches. In this study, preliminary phytochemical analysis of the ethylacetateleaf extract of Mitra...
19. HEPATOPROTECTIVE AND WOUND HEALING PROPERTIES OF METHANOLIC STEM BARK EXTRACT OF FICUS PLATYPHYLLA Del. Holl (MORACEA)
ABSTRACT
Ficus platyphylla (Fp) is a medicinal plant that is widely used in Northern part of Nigeria for the management of skin problems such as eczema and topical application of its gum (latex) to wounds. It is also used for treating malaria and psychosis. Its antioxidant, hepatoprotec...
20. SOLID DISPERSION AS AN APPROACH FOR SOLUBILITY AND DISSOLUTION ENHANCEMENT OF IBUPROFEN AND PIROXICAM
ABSTRACT
The aim of this study was to enhance the solubility and hence dissolution rate of two poorly soluble drugs: ibuprofen and piroxicam using Eudragit RS 100 and hydroxymethylpropylcellulose (HPMC) as carriers, by solid dispersion technique and to evaluate the effect of trona (sodi...
21. EFFECTS OF CO-ADMINISTRATION OF SITAGLIPTIN AND ETHANOL LEAF EXTRACT OF MORINGA OLEIFERA LAM. IN ALLOXAN-INDUCED DIABETES MELLITUS AND ITS CHRONIC COMPLICATIONS IN RATS
ABSTRACT
Incidence and prevalence of type 2 diabetes mellitus (T2DM), with its resultant complications continue to be on the increase. The outcome of management is highly dependent on efficacy, safety and suitability of medicines used concomitantly. An aspect of efficacy/safety that is...
22. EFFECTS OF VITAMIN B COMPLEX THERAPY ON TEMPORAL VARIATION IN GENTAMICIN NEPHROTOXICITY IN WISTAR RATS
ABSTRACT
The efficacy and toxicity of several drugs is circadian-rhythm dependent, and this can be exploited as a guide to ameliorate such drug toxicity. Gentamicin is an aminoglycoside antibiotic used in treatment of a variety of infections. Its use is however limited by its associated...
23. EVALUATION OF THE GASTROPROTECTIVE AND SUB-CHRONIC TOXICITY OF METHANOL STEM BARK EXTRACT OF XIMENIA AMERICANA LINN (OLACACEAE) IN MALE WISTAR RATS
Abstract
Ximenia americana is a plant used traditionally in northern parts of Nigeria for treatment of leprotic ulcers and mouth ulcers in addition to other medicinal uses. It contains flavanoids, saponins, tannins among others that has been reported to possess gastroprotective potentia...
24. PHYTOCHEMICAL AND ANTIVENOM EVALUATIONS OF METHANOL LEAF EXTRACT OF CLERODENDRUM CAPITATUM (WILLD) SCHUM. AND THONN. (VERBENACEAE)
ABSTRACT
Clerodendrum capitatum (Willd) Schumach and Thonn. is a common medicinal plant found mainly in the tropical and sub-tropical regions of the world where it is used in traditional medicine for the treatment of various conditions including erectile dysfunction, wounds, diabetes me...
25. SOME CARDIOVASCULAR ACTIVITIES OF THE AQUEOUS LEAF EXTRACT OF CROTON ZAMBESICUS LINN (EUPHORBIACEAE) IN LABORATORY ANIMALS
Abstract
Croton zambesicus Linn (Euphorbiaceae) is a highly valued medicinal plant in Nigeria and West African sub-region. It is used by traditional medicine practitioners in the treatment of various ailments including hypertension. This study aims to determine some cardiovascular activ...
26. SOME PHARMACOLOGICAL PROPERTIES OF METHANOL EXTRACT OF ANISOPUS MANNII N.E.Br (ASCLEPIADACEAE) IN ALLOXAN-INDUCED HYPERGLYCAEMIC WISTAR RATS
ABSTRACT
Diabetes mellitus is a metabolic disorder that affects carbohydrates, lipids and proteins resulting in sustained hyperglycaemia which could lead to serious organ(s) damage and death. The aim of this study was to investigate some of the pharmacological properties of the methanol...
27. TOXICITY STUDIES OF THE ETHANOLIC STEM BARK EXTRACT OF RANDIA NILOTICA STAPF. IN RATS
ABSTRACT
The use of medicinal plant extracts to maintain health, prevent or cure various diseases is known since ancient times. However, most times, there is little or no knowledge of the associated possible toxic injuries on vital organs morphology or functions from the use of such pla...
28. EFFECT OF RANITIDINE ON PHARMACOKINETIC PARAMETERS OF METRONIDAZOLE IN HEALTHY HUMAN VOLUNTEERS
ABSTRACT
Pharmacokinetics is the study of the time course of drug movement in the body during absorption, distribution, metabolism and elimination.Drug interactions are pharmacodynamic, pharmacokinetic, or clinical responses to the administration of a drugcombination that differs from t...
29. EVALUATION OF THE BINDING PROPERTIES OF ENZYME - HYDROLYZED CASSAVA STARCH IN CHLOROQUINE PHOSPHATE TABLET FORMULATIONS
ABSTRACT
Starch is a major carbohydrate, easily extractable from various sources like cassava, maize, potato etc which find wide application in various food and Pharmaceutical industries. There has been a lot of attempt to modify this highly flexible polymer with the aim of extending an...
30. PHYTOCHEMICAL AND INHIBITION STUDIES OF GARCINIA KOLA HECKEL (GUTTIFERAE) SEED EXTRACTS ON SOME KEY ENZYMES INVOLVED WITH DIABETES
ABSTRACT
Garcinia kola is an Angiosperm belonging to the family Guttiferae. It is known in commerce as bitter kola. The plant seeds have been used in the treatment of a wide range of diseases including diabetes, and its importance in folkloric medicine as a purgative, mastcatory, aphrod...
31. SOME NEUROPHARMACOLOGICAL STUDIES OF EXTRACT AND FRACTIONS OF CRINUM ZEYLANICUM(L.) (AMARYLLIDACEAE)BULB IN LABORATORY ANIMALS
ABSTRACT
Crinum zeylanicum is a medicinal plant used in folk medicine for management of general debility, infantile seizures and pain. Some neuropharmacological effects of methanolic bulb extract of Crinum zeylanicum were studied in laboratory animals.The Phytochemical screening of the...
32. STUDIES ON IN-VIVO ANTIOXIDANT AND HEPATOPROTECTIVE PROPERTIES OF CITRUS SINENSIS (L.) OSBECK PEEL EXTRACT IN WISTAR RATS
ABSTRACT
Citrus sinensis is the commonest, most widely cultivated and consumed citrus fruit. Large amounts of peel wastes are formed when citrus is consumed or processed; and suitable methods have to be adopted to utilize these waste materials for conversion into value-added products. F...
33. THE LEVEL OF MICROBIAL CONTAMINATION OF YOGHURTS
INTRODUCTION
Yoghurt is a cultural diary product produced by lactic fermentation of milk (Hui, 1992). Yoghurt is produced by the controlled fermentation of milk by two species of bacteria; Lactobacillus bulgaricus and<...
34. EVALUATION OF NOOTROPIC ACTIVITY OF METHANOL STEM EXTRACT OF PARQUETINA NIGRESCENS AFZEL IN MICE
ABSTRACT
Parquetina nigrescens is a plant with numerous ethnomedicinal uses in African traditional medicine practice. In the South Western part of Nigeria, the stems and roots are roasted, powdered then mixed with pap taken as memory enhancer and for its antiaging effect. This study the...
35. PREVALENCE AND ANTIMICROBIAL SUSCEPTIBILITY PROFILE OF BACTERIAL ISOLATES FROM CASES OF BACTERIURIA IN ABUJA AND ENVIRON
ABSTRACTS
Urinary tract infections (UTI) are systemic infections that pose great problem to the health care delivery system worldwide. More importantly, the uropathogenic isolates are becoming more resistant to commonly used antimicrobial agents. In order to evaluate the extent of signi...
36. THE EFFECT OF QUININE-ARTESUNATE CO-ADMINISTRATION ON SOME BIOCHEMICAL PARAMETERS IN PLASMODIUM BERGHEI PARASITIZED SWISS ALBINO MICE AND RATS
ABSTRACT
Malaria has been the leading cause of morbidity and mortality in most Sub-saharan Africa and Southeastern Asia. Combination therapy has been recommended for treatment of malaria and this could lead to drug-drug interaction. This work titled “The effect of Quinine-Artesuna...
37. THE PRODUCTION OF BIODIESEL (FAME) FROM PALM KERNEL OIL (PKO) USING CONCENTRATED SULPHURIC ACID AS CATALYST
STATEMENT OF RESEARCH PROBLEM
There has been several analytical works on biodiesel production using base catalyzed mechanism (usually sodium hydroxide or potassium hydroxide) or acid catalyzed mechanism (usually concentrated sulfuric acid). However, this research work i...
38. ANTIMICROBIAL EFFECTS OF HONEY AND ITS SPECIFIC ACTIONS ON CELL WALLS, MEMBRANES AND ENZYMES OF SOME MICROBIAL PATHOGENS
ABSTRACT
Antimicrobial agents of plant origin have enormous therapeutic potentials. Honey, which is a product of plant, is a sugary substance produced by bee from the nectar of flower. It has been an age long antimicrobial therapy for wounds and burns. The aim of this study was to deter...
39. ANTITRYPANOSOMAL EFFECT OF CRUDE SCORPION VENOM EXTRACT IN TRYPANOSOMA EVANSI INFECTED SWISS ALBINO RATS
ABSTRACT Despite the control measures against trypanosomiasis over the past few decades, the disease still contributes to the current economic losses and socio-political crises in the sub-Saharan Africa. The recent interest of chemotherapists in aggressive search for novel antitrypanosomal drug a...
40. CARDIO PROTECTIVE ACTIVITIES OF N-HEXANE EXTRACT OF DESMODIUM VELUTINUM STEM ON ALBINO WISTER RAT
ABTRACT
This study evaluates the cardio protactive effect of N-hexane extract of Desmodium Velutinum stem on albino wister rat. Rats used in this study were grouped into four and each group was fed differentely. Rats in group one, three, and four wre fed with the aid of a syringe withou...
41. PRELIMINARY INVESTIGATION ON EFFECTS OF BURANTASHI EXTRACT ON LIVER ENZYMES OF AIBINO MALE AND FEMALE WHISTAR RATS.
ABSTRACT
This work was carried out to investigate the effects of Burantashi extract on liver enzymes of albino male and female whistar rats. Burantashi is a popular seasoning agent to barbecued meat (suya) in Nigeria,mostly found in the northern part of the Nigeria. Liver Enzymes are th...
42. THE EFFECT OF ETHANOL EXTRACT OF DESMODIUM VELUTINUM STEM ON SOME MARKER EMZYME IN LIVER OF ALBINO WISTAR RATS
Abstract
Present investigations were carried out on the effect of ethanol extract of Desmodium velutinum stem on some liver enzymes of albino wistar rats fed with 8 high fat from cow‟s brain. Twelve healthy albino wistar rats were divided into four groups. Group I rats were fed with bal...
43. BIOCALCIFICATION OF CONCRETE USING CARBONIC ANYHDRASE PRODUCED BY SOIL BACTERIAL ISOLATES
ABSTRACT
Two (2) bacterial isolates obtained from Garima construction sites were named GARIMA (A) and (B), and code-named GA (A) and GA (B) respectively. They were screened for their carbonic anhydrase (CA) producing ability. Isolates GA (A) and GA (B) showed positive reaction to para-n...
44. CHARACTERIZATION OF UREASE OF BACTERIAL ISOLATES FROM CEMENT FOR CONCRETE ENHANCEMENT
ABSTRACT
Ureases are a group of enzymes that hydrolyse urea producing carbon dioxide and ammonia. Urease producing bacteria have shown their importance in microbially induced calcium carbonate precipitation in the construction industry. This study focused on the characterization of bact...
45. STUDIES ON YERSINIOSIS IN HUMAN AND SELECTED ANIMAL POPULATIONS IN JOS AND ITS ENVIRONS
ABSTRACT
Yersinia enterocolitica and Yersinia pseudotuberculosis are important food and water borne pathogens that has recently emerged world wide. This study was aimed at characterizing the prevalence of Yersinia enterocolitica and Yersinia pseudotuberculosis in human and selected anim...
46. DETECTION OF HEPATITIS B VIRUS FROM INMATES IN SELECTED CORRECTIONAL FACILITIES IN NIGER STATE
ABSTRACT
Research has shown high transmission of hepatitis B virus (HBV) among inmates in correctional facilities in the developed world, but the data base for the developing countries is still lacking information on same. The aim of this study was to determine the prevalence of Hepatit...
47. EVALUATION OF MOLLUSCICIDAL ACTIVITIES OF CRUDE AND ALKALOIDAL FRACTION OF ANOGEISSUS LEIOCARPUS (AFRICAN BITCH) AND PSEUDOCEDRELA KOTSCHYI (DRY ZONE CEDAR) ON VECTOR OF SCHISTOSOMIASIS
ABSTRACT
Over the years, the use of plant-based molluscicides has received substantial consideration in the satisfaction for cost-effective alternatives to chemotherapy and synthetic molluscicides in schistosomiasis control. This study was aimed at evaluating the molluscicidal potential...
48. IN VIVO EFFICACY OF METHANOLIC EXTRACTS OF ROOT AND LEAF OF Morinda lucida IN Plasmodium berghei - INFECTED MICE
ABSTRACT
Therapeutic effects of the methanolic root extract and a combination of leaf and root extracts of Morinda lucida were evaluated for antiplasmodial activities. The phytochemical screening of the methanolic root extract showed the presence of saponins, flavonoids, alkaloids, phen...
49. ANALYSIS OF PETROLEUM POLLUTION ON SERUM TRACE ELEMENT LEVEL, OXIDATIVE STATUS, AND BIOCHEMICAL INDICES IN THE RESIDENTS OF AN OIL HOST COMMUNITY (UGBEGUNGUN) IN DELTA STATE, NIGERIA
ABSTRACT
Activities of crude oil refining disrupt natural ecosystems which expose residents to environmental pollution, and consequently pose threat to their health and wellness. This study was aimed to analyze serum trace elements levels, oxidative status, and biochemical indices in th...
50. EVALUATION OF SOME NATURAL AND SYNTHETIC PRODUCTS AGAINST AFRICAN TRYPANOSOMIASIS
ABSTRACT
The chemotherapy of African trypanosomiasis, a fatal protozoal disease of man and animals is beset with many problems including a limited repertoire of expensive compounds, drug toxicity and resistance and protracted treatment protocols. In order to improve chemotherapy, some n...
