1. AN ANTIMICROBIAL AND PHYTOCHEMICAL STUDY OF LEAVES (A case study of Mangifera indica and Carica papaya)
ABSTRACT
Phytochemical and antimicrobial screening analysis of Mangifera indica and Carica papaya indicated the presence of alkaloid, saponin, flavonoid, steroid, tannin, phenol and glycoside. Extract of Mangifera indica and Carica papaya were investigated for their ant...
2. THE ROLE OF PLANTS IN THE TREATMENT OF DISEASES CAUSED BY MICRO-ORGANISMS BASED IN THE NATURAL PRODUCTS (pure and applied chemistry)
ABSTRACT
This study was carried out on the role of plants in the treatment of diseases caused by micro-organisms based in the natural products. The study was specifically carried out to determine the antibacterial effect of P. amarus and P. niruri, and determine t...
3. THE EFFECT OF THE ETHANOLIC EXTRACT OF ANCHOMANES DIFFORMIS (BLUME) ON LIVER FUNCTIONS OF ADULT WISTAR RATS
ABSTRACT
This research was carried out to determine the effect of administration of Achomanes Difformis (blume) on liver functions in adult wistar rat, in which 20 adult wistar rats were purchased at the institute of advanced medical research and training (IMRA...
4. AN EVALUATION OF THE APHRODISIAC AND FERTILITY ENHANCING EFFECT OF THE METHANOLIC ROOT EXTRACT OF CISSUS POPULNEA Guill.And Perr. (Vitaceae)
ABSTRACT
Aphrodisiac activity of Cissus populnea was assessed using physical, biochemical and psychological methods. Rats were randomized into five groups of six rats. The first group received normal saline (10ml/kg), the second, third and fourth groups received extract doses of 250mg/k...
5. ANALGESIC, ANTI-INFLAMMATORY AND TOXICITY STUDIES ON METHANOLIC LEAF EXTRACT OF ROTHMANNIA LONGIFLORA SALISB (RUBIACEAE) IN RATS AND MICE
ABSTRACT
The herbalists in several African Countries have used Rothmannia longiflora decoctions as febrifugal and analgesic agent. The present study examined the analgesic, anti-inflammatory and toxicological profile of the methanolic extract of the plant in experimental animals. The pr...
6. HEPATOPROTECTIVE AND WOUND HEALING PROPERTIES OF METHANOLIC STEM BARK EXTRACT OF FICUS PLATYPHYLLA Del. Holl (MORACEA)
ABSTRACT
Ficus platyphylla (Fp) is a medicinal plant that is widely used in Northern part of Nigeria for the management of skin problems such as eczema and topical application of its gum (latex) to wounds. It is also used for treating malaria and psychosis. Its antioxidant, hepatoprotec...
7. HYPOTENSIVE ACTIVITY AND TOXICOLOGICAL PROFILE OF STEM BARK EXTRACT OF SYZYGIUM GUINEENSE (Willd, D.C. Myrtaceae) IN LABORATORY ANIMALS
ABSTRACT
Hypertension of unknown cause is called essential or primary hypertension while hypertension of a known cause is called secondary hypertension. Hypertension is called a silent killer because it is usually asymptomatic. It is a global problem affecting 1 in 3 adults in the Unite...
8. PHARMACOGNOSTIC AND ANTIBACTERIAL STUDIES OF THE LEAVES OF CHROMOLAENA ODORATA (L.) KING & ROBINSON (ASTERACEAE)
ABSTRACT
The plant, Chromolaena odorata (L.) King & Robinson is a member of the Asteraceae family. It grows abundantly in Southern Nigeria where its leaves are used as traditional herbal treatment for wounds and fevers. The plant, C. odorata was therefore investigated for antibacter...
9. PHYTOCHEMICAL AND SOME PHARMACOLOGICAL STUDIES OF THE LEAF, STEM BARK AND ROOT BARK EXTRACTS OF STACHYTARPHETA ANGUSTIFOLIA (MILL) VAHL. (VERBENACEAE
ABSTRACT
The extracts of the leaf, stem bark and root bark of Stachytarpheta angustifolia (Mill) Vahl. (Verbenaceae), were subjected to preliminary phytochemical screening and the result revealed the presence of carbohydrates, steroids, cardiac glycosides, terpenoids, flavonoids, tannin...
10. PHYTOCHEMICAL AND ANTI-INFLAMMATORY STUDIES OF N-BUTANOL SOLUBLE FRACTION OF THE METHANOLIC EXTRACT OF THE AERIAL PARTS OF INDIGOFERA HIRSUTA LINN (LEGUMINOSAE)
Abstract
Indigofera hirsuta Linn. (Leguminosae) is a well-known plant used in African traditional medicine as an anti-inflammatory, antibacterial, antiulcer, anti-venom and anticonvulsant. The air-dried aerial parts of I. hirsuta was extracted with methanol using a soxhlet extractor and...
11. PHYTOCHEMICAL AND ANTIVENOM STUDIES ON THE STEM BARK OF ALBIZIA CHEVALIERI HAMS (MIMOSACEAE) ON NAJA NIGRICOLLIS BROADLEY ENVENOMATED MICE
ABSTRACT
Albizia chevalieri Hams (Mimosaceae), mostly found in the Northern Sahel Savannah region of Nigeria as well as in Nigér and Senegal is a tree of the acacia type with a long list of folklore therapeutic claims which include its use as purgative, taenicidal, cough remedy,...
12. PHYTOCHEMICAL AND SOME PHARMACOLOGICAL STUDIES OF THE AERIAL PART OF ALYSICARPUS OVALIFOLIUS Schumach & Thonn FAMILY: FABACEAE
ABSTRACT
Alysicarpus ovalifolius (Schum.&Thonn) Family: Fabaceae is a protein rich fodder plant that is widely distributed across Africa, Asia and Australia and medicinally used to treat cough and wounds. Recently, it has been reported to be used in the Northern part of Nigeria as t...
13. Phytochemical and Some Pharmacological Studies on the Stem Bark of Anogeissus lieocarpus (Combretacea)
Abstract
The plant Anogeissus lieocarpus (Combretacea), is a plant widely used in Africa as a remedy for abdominal pains, cough and chest pain. The plant is also beneficial in leprosy, malaria, anthelmentic, fungal and bacterial infections. The bark of Anogeissus lieocarpus was screened...
14. PHYTOCHEMICAL, ANTIHYPERTENSIVE AND ANTIMICROBIAL STUDIES ON THE STEM BARK EXTRACT OF STEREOSPERMUM KUNTHIANUM CHAM (BIGNONIACEAE)
Abstract
Stereospermum kunthianum (Family: Bignoniaceae) plant is used in Hausa ethnomedicine in treating bronchitis, veneral diseases, diarrheoa and dysentery. It is also used in the treatment of ulcers, leprosy, skin eruptions, respiratory ailments, abortifacient, antihypertensive and...
15. PHYTOCHEMICAL, PHARMACOLOGICAL AND FORMULATION STUDIES OF Andrographis paniculata Nee Acanthacae
ABSTRACT
The leaves of Andrographis paniculata acanthaceae is used locally in Northern Nigerian for the treatment of hypertension without quantification or dosage standardization. This work was primarily set out to find justification for the local medicinal use of this plant and to scie...
16. SOME NEUROPHARMACOLOGICAL AND TOXICOLOGICAL STUDIES OF THE ETHANOLIC LEAF EXTRACT OF CUSSONIA BARTERI SEEMAN (ARALIACEAE) IN LABORATORY ANIMALS
ABSTRACT
Cussonia barteri is used in traditional medicinefor the management of convulsion and epilepsy, especially in children in Ghana and Nigeria. Literature survey revealed that the safety and efficacy of such important medicinal plant have not been scientifically validated. In the p...
17. SOME PHARMACOLOGICAL STUDIES ON THE ETHANOLIC STEM BARK EXTRACT OF PTEROCARPUS ERINACEUS POIR (FABACEAE)
ABSTRACT
Some pharmacological effects of the 70% ethanolic stem bark extract of Pterocarpus erinaceus were investigated in experimental animals. Preliminary Phytochemical studies of the ethanolic extract revealed the presence of Tannins, Carbohydrates, Proteins & Amino acids, Flavon...
18. STUDIES ON ANTIHAEMORRHAGIC AND ANTIBACTERIAL PROPERTIES OF BULB JUICE, ETHANOL AND AQUEOUS EXTRACTS OF ALLIUM SATIVUM LINN. (LILLIACEAE) AGAINST MENINGEAL BACTERIA
ABSTRACT
Bacterial meningitis (BM) is a devastating air-borne infectious disease of humans that causes cellular hemorrhagic sepsis, metabolic, neurologic and endocrine disorders and constitutes a serious threat to public health. Where malnutrition is linked to BM, it is a great economic...
19. DIURETIC AND TOXICITY STUDIES OF METHANOL STEM BARK EXTRACT OF SPONDIAS MOMBIN LINN (ANACARDIACEAE) IN RATS
ABSTRACT
Spondias mombin belongs to the family Anacardiacae. All parts of the tree are reported to be medicinally useful. The fruit juice is drunk as a diuretic and febrifuge. The main aim of the study is to determine the diuretic activity and toxicity of methanol stem bark extract of S...
20. ETHNOBOTANICAL SURVEY OF PLANTS USED FOR THE TREATMENT OF TYPHOID FEVER IN NIGERIA, AND EVALUATION OF ANTI-TYPHOID ACTIVITY OF TERMINALIA AVICENNOIDES GUILL & PERR. (COMBRETACEAE)
ABSTRACT
An ethnobotanical survey was conducted from December 2011 to April 2012 in Minna, Niger State, Nigeria. The survey was aimed at identifying and documenting medicinal plants used for the treatment of typhoid fever in 6 communities in Minna, Niger State and establishing resourcef...
21. PHYTOCHEMICAL SCREENING AND ANTICONVULSANT STUDIES OF ETHYL ACETATE FRACTION OF ETHANOLIC EXTRACT OF THE LEAVES OF GLOBIMETULA BRAUNII (LORANTHACEAE) PARASITING ON PILIOSTIGMA THONINGII (FABACEAE)
ABSTRACT
The ethyl acetate soluble fraction of ethanol extract of leaves of Globimetula braunii, a plant used in ethnomedicine for the treatment of epilepsy and diabetes among other ailments, was subjected to phytochemical and anticonvulsant screening. The phytochemical techniques emplo...
22. TOXICITY STUDIES OF THE ETHANOLIC STEM BARK EXTRACT OF RANDIA NILOTICA STAPF. IN RATS
ABSTRACT
The use of medicinal plant extracts to maintain health, prevent or cure various diseases is known since ancient times. However, most times, there is little or no knowledge of the associated possible toxic injuries on vital organs morphology or functions from the use of such pla...
23. PHARMACOGNOSTIC AND ANTIDIARRHOEA ACTIVITY OF LEAVES OF BAUHINIA RUFESCENS LAM (CAESALPINIOIDEAE)
ABSTRACT
Bauhinia rufescens Lam (Caesalpinioidae) is a scandent shrub or small tree measuring between 1-3m high but sometimes up to 8m high, often scraggy, stunted and multistemmed. The leaves are stomachic, anti-diarrheotic and anti-dysentric. This study is on the pharmacognostic, phyt...
24. PHARMACOGNOSTIC AND ANTI-INFLAMMATORY STUDIES OF THE LEAVES OF ALLOPHYLUS AFRICANUS BEAUV (SAPINDACEAE)
ABSTRACT
This study evaluated some pharmacognostic standards and anti-inflammatory activity of the leaves of Allophylus africanus Beauv (Sapindaceae). The plant has a wide distribution in West Africa, with Nigeria (Mambila Plateau, Calabar) inclusive. It has been used in communities for...
25. PHARMACOGNOSTIC AND BIOLOGICAL EVALUATON OF THE ROOT BARK OF SABA COMORENSIS (BOJ.) PICHON (APOCYNACEAE)
ABSTRACT
Saba comorensis (Boj) Pichon (Apocynaceae) has been used traditionally in various parts of Tropical Africa region as an aphrodisiac, for rheumatism, arthritis, liver disease, jaundice, venereal disease, normal spleen function, as laxative, and purgative. This study is aimed at...
26. PHARMACOGNOSTIC AND SOME BIOLOGICAL STUDIES ON MAYTENUS SENEGALENSIS (LAM.) EXELL (CELASTRACEAE)
ABSTRACT
Maytenus senegalensis (Celastraceae) is commonly known as thorny staff tree or confettii tree, is of high traditional use among the „Hausa‟ community of Northern Nigeria. Hence the present investigation was to establish the pharmacognostic parameters for the leaves and st...
27. SOME NEUROPHARMACOLOGICAL STUDIES OF EXTRACT AND FRACTIONS OF CRINUM ZEYLANICUM(L.) (AMARYLLIDACEAE)BULB IN LABORATORY ANIMALS
ABSTRACT
Crinum zeylanicum is a medicinal plant used in folk medicine for management of general debility, infantile seizures and pain. Some neuropharmacological effects of methanolic bulb extract of Crinum zeylanicum were studied in laboratory animals.The Phytochemical screening of the...
28. SUSCEPTIBILITY PROFILES OF SOME BACTERIA ISOLATED FROM STOOL OF DIARRHOEAL PATIENTS TO THE STEM AND ROOT BARKS EXTRACTS OF FICUS SYCOMORUS Linn (Moracae)
ABSTRACT
Effective antibiotic management of diarrhoea caused by bacterial organisms faces challenge of antibiotic resistance which combines to pose serious problems. Local people often use some plants to treat diarrhoea. The efficacy of one of such plant is the subject of this investiga...
29. EVALUATION OF AQUEOUS AND METHANOL ROOT EXTRACTS OF CALOTROPIS PROCERA AIT (ASCLEPIADACEAE) FOR ANTI-ASTHMATIC ACTIVITY ON WISTAR RATS AND GUINEA PIG ILEUM
ABSTRACT
Asthma, which affects an estimated 300 million people worldwide, is an incurable health disorder of a major public health concern globally. The present orthodox therapy for asthma has several drawbacks including many undesirable side effects and high cost of management (especia...
30. PHARMACOLOGICAL EVALUATION OF THREE LOCALLY USED MEDICINAL PLANTS AGAINST CARBON TETRACHLORIDE-INDUCED HEPATOTOXICITY IN RATS
ABSTRACT
Drugs from plant and animal sources are increasingly becoming important in the therapeutic management of liver diseases. This study was undertaken to evaluate the prophylactic and curative effects of methanolic extracts of Balanites aegyptiaca root, Boswellia dalzielii stem bar...
31. PHYTOCHEMICAL AND ANTI BACTERIAL STUDIES ON THE STEM BARK OF LANNEA BARTERI. (OLIV.) ENGL. (ANACARDIACEAE)
ABSTRACT
Lannea bartei (Oliv.) Engl. is a plant with medicinal and commercial uses found usually in the tropical regions like Africa especially Ivory Coast. The plant is used traditionally to treat various diseases including wound healing and as anti diarrhoea. This research is aimed at...
32. PHYTOCHEMICAL AND BIOLOGICAL STUDIES ON THE SEEDS OF JATROPHA CURCAS LINN. (EUPHORBIACEAE)
ABSTRACT
Jatropha curcas Linn. (Euphorbiaceae) is a shrub that grows up to 5m in height. It thrives well in tropical countries. It grows in the wild as an uncultivated, non-food plant. It is traditionally used as a living fence to protect gardens from animals. An ethnobotanical survey o...
33. PHYTOCHEMICAL AND PHARMACOLOGICAL STUDIES ON THE LEAF EXTRACT OF STEREOSPERMUM KUNTHIANUM (BIGNONIACEAE)
ABSTRACT
Stereospermum kunthianum (Bignoniacea) herb is used in Hausa ethnomedicine in treating bronchitis, veneral diseases, diarrheoa and dysentery. It is also used in the treatment of ulcers, leprosy, skin eruptions, respiratory ailments and gastritis. The plant is common in Northern...
34. SOME NEUROPHARMACOLOGICAL PROPERTIES OF METHANOLIC STEM BARK EXTRACT OF FICUS INGENS (MIQUEL) MIQUEL IN MICE AND CHICKS
ABSTRACT
Ficus ingens (Miquel) Miquel belongs to the Moraceae family. In some African countries, extracts of the bark are administered to cows with a low milk production, and to people suffering from anaemia, piles and diarrhea. The behavior of living organisms is a visible manifestatio...
35. ANTIBACTERIAL ACTIVITY OF HELIANTHUS ANNUUS SEEDS EXTRACT ON SALMONELLA SPECIES AND ESCHERICHIA COLI
ABSTRACT Medicinal plants contain active ingredients with therapeutic values. Helianthus annuus L (Asteraceae) commonly referred to as “sunflower” has been reportedly used in managing and treating some ailments over the years. This study investigated the in vitro and in vivo antibacte...
36. EVALUATION OF ANTIFUNGAL EFFICACY OF SOME LEAF EXTRACTS OF SOME PLANTS ON RED ROT PATHOGEN (Colletotrichum falcatum) OF SUGARCANE (Saccharum officinarum)
ABSTRACT
Botanical extracts have shown appreciable achievement in controlling plant diseases. This became evident in this study when the potency of leaf extracts from Azadirachta indica, Carica papaya, Lawsonia inermis, Khaya senegalensis and Ziziphus spina- christi were tested on the m...
37. IN VIVO EFFICACY OF METHANOLIC EXTRACTS OF ROOT AND LEAF OF Morinda lucida IN Plasmodium berghei - INFECTED MICE
ABSTRACT
Therapeutic effects of the methanolic root extract and a combination of leaf and root extracts of Morinda lucida were evaluated for antiplasmodial activities. The phytochemical screening of the methanolic root extract showed the presence of saponins, flavonoids, alkaloids, phen...
38. PHARMACOLOGICAL EFFECTS OF METHANOLIC EXTRACT OF GARCINIA KOLA (HECKEL) SEED ON THE REPRODUCTIVE PROFILES OF SOME MALE EXPERIMENTAL ANIMALS
ABSTRACT
Garcinia kola is commonly consumed in Nigeria in social ceremonies and for leisure purposes. It is speculated to enhance sexual performance in males. The effects of methanolic extract of Garcinia kola seed on the male reproductive profiles of rats were determined at oral doses...
39. ANTIPLASMODIAL ACTIVITY OF AQUEOUS AND ETHANOLIC EXTRACTS OF ANACARDIUM OCCIDENTALE AND CYMBOPOGON CITRATUS
ABSTRACT
The search for antimalarial compounds was necessitated by Plasmodium falciparum resistance to most antimalarial drugs. In endemic countries where malaria is prevalent, medicinal plants are often used to treat malaria. In this study, the in vitro antimalarial activities of crude...
40. ANTIDIABETIC PROPERTIES OF MUCUNA PRURIENS L. (D.C.) SEED EXTRACT AND ITS TABLET FORMULATIONS
ABSTRACT
Diabetes mellitus and its complications continue to be one of the highest causes of morbidity and mortality in recent times. Although many drugs are commercially available for use in the management of diabetes, their side effects and high costs underscore the need for new drugs...
