1. AMELIORATIVE EFFECT OF RESVERATROL ON LEAD-INDUCED ORGAN TOXICITY IN WISTAR RATS
ABSTRACT
Resveratrol is a potent antioxidant found abundantly in grapes and in lesser quantities in peanuts, fruits and other food items. Dozens of reports have shown that resveratrol prevents or slows the progression of a wide variety of illnesses including cancer (col...
2. SURFACE ACTIVITY AND RELEASE PROPERTIES OF SOME TROPICAL GUMS IN ARTEMETHER AND ARTESUNATE SODIUM TABLET FORMULATIONS
ABSTRACT
Plant gums are natural polymers with low toxicity, high biodegradability and high compatibility with drugs making them useful as pharmaceutical excipients in solid, semi-solid and liquid formulations. This work was aimed at evaluating the surface activity and release properties...
3. EVALUATION OF THE BINDING AND SUSPENDING PROPERTIES OF BAGGASE-DERIVED METHYLCELLULOSE
ABSTRACT
Sourcing of raw materials for use in pharmaceutical industries is a continuing challenge. Excipients, which form the bulk of a dosage form, are derived either from natural sources or synthesized wholly or semi-synthesized. The absence of an ideal excipient material continues to...
4. THE USE OF GELATIN-ACACIA CO-PRECIPITATE (GELAC) IN THE FORMULATION OF SUSTAINED RELEASE MATRIX TABLETS OF DICLOFENAC SODIUM
ABSTRACT
Gums find application in tablet formulation as binder because of their adhesive nature. Natural gums are promising biodegradable polymeric materials. The aim of this study was to prepare a gelatin and acacia co-precipitate (GelAc) to be used as a release retardant in the formul...
5. AFFINITY AND REACTIVITY STUDIES OF THE REACTION OF HUMAN (Homo sapiens) AND CAT (Felis catus) HAEMOGLOBINS WITH 5,5´-DITHIOBIS(2-NITROBENZOATE)
ABSTRACT
Some haemoglobins have high oxygen affinity (high-affinity) while others have low oxygen affinity (low-affinity) as exemplified in human and cat haemoglobins respectively. High-affinity haemoglobins bind organic phosphates strongly and this lowers their oxygen affinities and th...
