1. ASSESSING THE ORAL HEALTH RECORDS AND ANTIBIOGRAM OF ANAEROBIC BACTERIA ISOLATES FROM PATIENTS VISITING DENTAL UNIT OF AHMADU BELLO UNIVERSITY MEDICAL CENTER, ZARIA
ABSTRACT
Oral health can be a good indicator of general health and has been linked to systemic diseases, therefore, maintaining good oral hygiene is important. Oral infections are polymicrobial with dental caries and periodontal disease being the major oral conditions affecting the publ...
2. COMPARATIVE BIOEQUIVALENCE STUDIES OF SOME BRANDS OF METRONIDAZOLE TABLETS MARKETED IN ZARIA, NIGERIA
ABSTRACT
Multisource pharmaceutical products are intended to be pharmaceutically equivalent or pharmaceutical alternatives that are bioequivalent and hence are therapeutically equivalent and interchangeable. Thus, this study was aimed at carrying out a comparative in-vitro and in-vivo b...
3. COMPARATIVE IN-VITRO BIOEQUIVALENCE STUDIES OF SOME BRANDS OF METRONIDAZOLE TABLET MARKETED IN ZARIA, KADUNA STATE
ABSTRACT
Metronidazole is an antibacterial and antiprotozoal drug used in the treatment of amebiasis, giardiasis, trichomoniasis and other microbial diseases. It is an essential drug commonly found in Nigerian market and has so many generics and dosage forms under various trade names by...
4. EVALUATION OF TABLETING AND COMPRESSIONAL CHARACTERISTICS OF NATIVE AND MICROCRYSTALLINE STARCHES DERIVED FROM DIGITARIA IBURUA
ABSTRACT
Acid hydrolyzed starch produces microcrystalline starch (MCS) with improved functional properties in terms of flowability or compressibility. The aim of this study was to investigate the binder, disintegrant and compressional properties of native and modified starches derived f...
5. EVALUATION OF MODIFIED FINGER MILLET STARCH (Eleusinecoracana L.) AS FILLER/BINDER IN DIRECT COMPRESSION
ABSTRACT
Starch modifications are a means of altering the structure and affecting the hydrogen bonding in a controllable manner to enhance and extend their application. There are different methods for modification of starch such as chemical modifications which include stabilization, cro...
6. EVALUATION OF THE BINDING AND SUSPENDING PROPERTIES OF BAGGASE-DERIVED METHYLCELLULOSE
ABSTRACT
Sourcing of raw materials for use in pharmaceutical industries is a continuing challenge. Excipients, which form the bulk of a dosage form, are derived either from natural sources or synthesized wholly or semi-synthesized. The absence of an ideal excipient material continues to...
7. DEVELOPMENT OF A FILLER-BINDER DISINTEGRANT FOR DIRECT COMPRESSION TABLETING BY CO-PROCESSING MICROCRYSTALLINE CELLULOSE AND CROSPOVIDONE
ABSTRACT
The aim of the study was to improve the disintegration functionality of microcrystalline cellulose (MCC) as a direct compression excipient in tablet formulation by coprocessing MCCwith crospovidone (CPV), a superdisintegrant. Design of Experiment (DoE) approach was adopted to o...
8. EFFECT OF RANITIDINE ON PHARMACOKINETIC PARAMETERS OF METRONIDAZOLE IN HEALTHY HUMAN VOLUNTEERS
ABSTRACT
Pharmacokinetics is the study of the time course of drug movement in the body during absorption, distribution, metabolism and elimination.Drug interactions are pharmacodynamic, pharmacokinetic, or clinical responses to the administration of a drugcombination that differs from t...
9. EVALUATION OF A CO-PROCESSED EXCIPIENT FROM COW BONE POWDER AND GELATIN FOR USE IN DIRECT COMPRESSION TABLETING
ABSTRACT
The objective of the study was to develop an excipient consisting of cow bone powder and gelatin by the co-processing method and to evaluate its use in direct compression tablet formulation. Co-processing is based on the novel concept of two or more excipients interacting at th...
10. FORMULATION STUDIES OF ACACIA SIEBERIANA GUM IN CHOROQUINE AND METRONIDAZOLE MATRIX TABLETS
ABSTRACT
The crude plant gum from African Acacia sieberiana was purified and investigated for use as a matrix excipient for chloroquine phosphate and metronidazole tablet formulations. The chromatographic analysis of the acid hydrolysed gum revealed the presence of rhamnose, galactose,...
