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1. EFFECTS OF VITAMIN B COMPLEX THERAPY ON TEMPORAL VARIATION IN GENTAMICIN NEPHROTOXICITY IN WISTAR RATS

ABSTRACT

The efficacy and toxicity of several drugs is circadian-rhythm dependent, and this can be exploited as a guide to ameliorate such drug toxicity. Gentamicin is an aminoglycoside antibiotic used in treatment of a variety of infections. Its use is however limited by its associated...

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