1. AN APPRAISAL OF THE OMICRON VARIANT OF COVID-19 IN NIGERIA
1.1 BACKGROUND OF THE STUDY
The coronavirus disease 2019 (covid-19), which was discovered in Wuhan, China, in December 2019, has spread fast to practically every corner of the world Lorfa (2020). The condition is caused by the severe acute respiratory syndrome Coronavir...
2. A STUDY ON GARLIC (Allium sativum L.) MEAL AND ITS EFFECT AS A FEEDING INGREDIENT IN BROILER CHICKEN DIET
BACKGROUND OF THE STUDY
Because of the alleged harmful consequences of antibiotic resistance on human health, there is growing demand to decrease or abolish the use of antibiotics in poultry feed (Javandel et al., 2008). A nationwide regulation prohibit...
3. EVALUATION OF ANTIOXIDANT POTENTIAL OF MONODORA MYRISTICA (AFRICAN NUTMEG)
BACKGROUND OF THE STUDY
Lipid oxidation is one of the major reasons that food deteriorate and is caused by the reaction of fat and oil with molecular oxygen, leading to off-flavours that are generally called rancidity(Basturk et al., 2...
4. ASSESSING THE CAUSES OF DRUG ABUSE AND ITS EFECTS AMONG SCONDARY SCHOOL STUDENTS
BACKGROUND TO THE STUDY
Drug abuse is a social problem of great concern in our society like other social problems; drug abuse has been attracting the attention of sociologist, political scientist, psychologist, philosophers, criminologist and social workers.
...
5. AN ANTIMICROBIAL ANALYSIS AND PHYTOCHEMICAL OF Mangifera indica AND Carica papaya LEAVES
BACKGORUND TO THE STUDY
It is well known that in order for a plant to protect itself, it creates certain compounds that can also protect humans from sickness. Today, there are approximately 4000 distinct phytochemicals that have the potential to alter disorders such as...
6. ASSESSMENT ON THE ROLE OF PLANTS IN THE TREATMENT OF DISEASES CAUSED BY MICRO-ORGANISMS BASED IN THE NATURAL PRODUCTS
BACKGROUNG OF STUDY
Infectious diseases are a significant cause of morbidity and mortality worldwide, accounting for approximately 50% of all deaths in tropical countries and as much as 20% of deaths in the Americas. Despite the significant progress made in microb...
7. EVALUATION OF GLYCERINE RECOVERY FROM SPENT SOAP LYE PRODUCTION
BACKGROUND OF THE STUDY
Glycerine (propan 1, 2, 3 triol) is a discovered soluble in soap lye and as a residue in crude soap following the saponification of fats and oils with caustic soda. Traditionally, the process of soap production from fats and oils provides g...
8. EFFECT OF A TRAINING PROGRAMME ON KNOWLEDGE AND PRACTICE OF LIFESTYLE MODIFICATION AMONG HYPERTENSIVE PATIENTS ATTENDING OUT-PATIENT CLINICS IN LAGOS
ABSTRACT
Hypertension is the most common non-communicable disease and the leading cause of cardiovascular disease in the world. Many people with hypertension are unaware of their condition making treatment infrequent and inadequate. According to Seven Joint National Com...
9. REVIEWING THE NUTRITIONAL AND PHARMACOLOGICAL IMPORTANCE IN COMMON VEGETABLES IN NIGERIA.
Abstract
This research work was aimed at reviewing the nutritional and pharmacological importance in the common vegetables we eat in Nigeria. This work gives the detail study on the nutrient and non-nutritive elements that are present in the common leafy vegetables suc...
10. AMELIORATIVE EFFECT OF RESVERATROL ON LEAD-INDUCED ORGAN TOXICITY IN WISTAR RATS
ABSTRACT
Resveratrol is a potent antioxidant found abundantly in grapes and in lesser quantities in peanuts, fruits and other food items. Dozens of reports have shown that resveratrol prevents or slows the progression of a wide variety of illnesses including cancer (col...
11. ANALGESIC, ANTI-INFLAMMATORY AND OTHER PHARMACOLOGICAL ACTIVITIES OF METHANOL LEAF EXTRACT OF OLAX SUBSCORPIOIDEA OLIV (OLACACEAE) IN LABORATORY ANIMALS
ABSTRACT
Synthetic analgesic and anti-inflammatory drugs have major side effects such as constipation, nausea and vomiting, sedation and mental clouding, etc.,which have significantly limited their use.There is therefore, an intensification of search for newer analgesic and anti-inflamm...
12. ANTI-DIARRHOEAL AND SUBCHRONIC TOXICITY STUDIES ON METHANOL STEM BARK EXTRACT OF IRIVINGIA WOMBOLU VERMOESEN (IRVINGIACEAE) IN LABORATORY ANIMALS
Abstract
Irvingia wombolu is one of the herbal plants used as food for its nutritional values. It is also used as medicinal plant in the south-south and south-eastern part of Nigeria for the management of diarrhoea and other ailments. Although these medicinal plants are believed to be h...
13. ANTICONVULSANT STUDIES OF THE METHANOL EXTRACT AND FRACTIONS OF CASSIA SIAMEA LAM. (FABACEAE) IN MICE AND CHICKS
ABSTRACT
Cassia siamea is a shrub belonging to the Fabaceae family, native of Southeast Asia. The plant is commonly used in traditional medicine to treat hypertension, malaria and diabetes. Due to the easy cultivation of the plant, its widespread and also remarkable biological activitie...
14. ASSESSMENT OF THE PHARMACOLOGICAL INTERVENTIONS IN PREVENTION OF MOTHER TO CHILD TRANSMISSION (PMTCT) OF HIV/AIDS IN NASARA TREATMENT AND CARE CENTRE, AHMADU BELLO UNIVERSITY TEACHING HOSPITAL, ZARIA-NIGERIA
ABSTRACT
This study was undertaken in Nasara Treatment and Care Centre ABUTH Zaria, to assess the effect of pharmacological interventions in prevention of mother to child transmission (PMTCT) of HIV/AIDS. It is a combined prospective and retrospective study. The prospective component co...
15. APHRODISIAC AND REPRODUCTIVE STUDIES ON METHANOL ROOT BARK EXTRACT OF SECURINEGA VIROSA (ROXB. EX. WILLD.) BAILL IN MALE WISTAR RATS
ABSTRACT
Securinega virosa (SV) is a widely used plant in traditional medicine. The root is used as an aphrodisiac in north western Nigeria. The aim of the study was to provide pharmacological rationale for the ethnomedical use of the root of Securinega virosa as aphrodisiac as well as...
16. PHARMACOGNOSTIC AND ANTICONVULSANT STUDIES ON GLOSSONEMA BOVEANUM DECNE (APOCYNACEAE)
ABSTRACT
Glossonema boveanum Decne is a hairy canescent perennial herb belonging to the Apocynaceae. Traditionally, the powdered whole plant is use for the treatment of many illnesses including epilepsy. This study is aimed at establishing some of the pharmacognostic features of the pow...
17. PHARMACOLOGICAL INTERACTION BETWEEN ETHANOL EXTRACT OF MORINGA OLEIFERA LEAVES AND METFORMIN IN ALLOXANINDUCED HYPERGLYCAEMIC WISTAR RATS
Abstract
Herbs with anti-diabetic activity could initiate interactions if used concurrently with orthodox drugs. Moringa oleifera is one of such herbs usually taken as an adjunct to orthodox oral hypoglycaemic agents. This study investigated the possible pharmacological interaction betw...
18. PHARMACOTHERAPEUTICS OF MOOD DISORDERS IN PATIENTS ATTENDING NEURO PSYCHIATRIC CLINIC, AHMADU BELLO UNIVERSITY TEACHING HOSPITAL (ABUTH) ZARIA-NIGERIA
ABSTRACT
Mood disorders (primary major depressive disorder and bipolar affective disorder) constitute one of the world’s greatest public health problems and are associated with significant reductions in productivity, health and longevity. This study involved a retrospective analys...
19. PHYTOCHEMICAL AND SOME PHARMACOLOGICAL STUDIES OF THE LEAF, STEM BARK AND ROOT BARK EXTRACTS OF STACHYTARPHETA ANGUSTIFOLIA (MILL) VAHL. (VERBENACEAE
ABSTRACT
The extracts of the leaf, stem bark and root bark of Stachytarpheta angustifolia (Mill) Vahl. (Verbenaceae), were subjected to preliminary phytochemical screening and the result revealed the presence of carbohydrates, steroids, cardiac glycosides, terpenoids, flavonoids, tannin...
20. PHYTOCHEMICAL AND SOME PHARMACOLOGICAL STUDIES OF THE AERIAL PART OF ALYSICARPUS OVALIFOLIUS Schumach & Thonn FAMILY: FABACEAE
ABSTRACT
Alysicarpus ovalifolius (Schum.&Thonn) Family: Fabaceae is a protein rich fodder plant that is widely distributed across Africa, Asia and Australia and medicinally used to treat cough and wounds. Recently, it has been reported to be used in the Northern part of Nigeria as t...
21. PHYTOCHEMICAL AND SOME PHARMACOLOGICAL STUDIES ON THE LEAF EXTRACT OF ZIZIPHUS MUCRONATA WILLD. (RHAMNACEAE)
ABSTRACT
Chronic inflammation has been implicated in most non-communicable/chronic degenerative diseases including age-related cancers. Ziziphus mucronata, a plant used in ethnomedicine to treat different painful and inflammatory conditions, was subjected to phytochemical investigation...
22. Phytochemical and Some Pharmacological Studies on the Stem Bark of Anogeissus lieocarpus (Combretacea)
Abstract
The plant Anogeissus lieocarpus (Combretacea), is a plant widely used in Africa as a remedy for abdominal pains, cough and chest pain. The plant is also beneficial in leprosy, malaria, anthelmentic, fungal and bacterial infections. The bark of Anogeissus lieocarpus was screened...
23. PHYTOCHEMICAL, PHARMACOLOGICAL AND FORMULATION STUDIES OF Andrographis paniculata Nee Acanthacae
ABSTRACT
The leaves of Andrographis paniculata acanthaceae is used locally in Northern Nigerian for the treatment of hypertension without quantification or dosage standardization. This work was primarily set out to find justification for the local medicinal use of this plant and to scie...
24. SOME NEUROPHARMACOLOGICAL AND TOXICOLOGICAL STUDIES OF THE ETHANOLIC LEAF EXTRACT OF CUSSONIA BARTERI SEEMAN (ARALIACEAE) IN LABORATORY ANIMALS
ABSTRACT
Cussonia barteri is used in traditional medicinefor the management of convulsion and epilepsy, especially in children in Ghana and Nigeria. Literature survey revealed that the safety and efficacy of such important medicinal plant have not been scientifically validated. In the p...
25. SOME PHARMACOLOGICAL STUDIES ON THE ETHANOLIC STEM BARK EXTRACT OF PTEROCARPUS ERINACEUS POIR (FABACEAE)
ABSTRACT
Some pharmacological effects of the 70% ethanolic stem bark extract of Pterocarpus erinaceus were investigated in experimental animals. Preliminary Phytochemical studies of the ethanolic extract revealed the presence of Tannins, Carbohydrates, Proteins & Amino acids, Flavon...
26. STUDIES ON ANTIHAEMORRHAGIC AND ANTIBACTERIAL PROPERTIES OF BULB JUICE, ETHANOL AND AQUEOUS EXTRACTS OF ALLIUM SATIVUM LINN. (LILLIACEAE) AGAINST MENINGEAL BACTERIA
ABSTRACT
Bacterial meningitis (BM) is a devastating air-borne infectious disease of humans that causes cellular hemorrhagic sepsis, metabolic, neurologic and endocrine disorders and constitutes a serious threat to public health. Where malnutrition is linked to BM, it is a great economic...
27. TOXICOLOGICAL, ANTIPYRETIC, ANALGESIC AND ANTI-INFLAMMATORY PROPERTIES OF METHANOL LEAF EXTRACT OF DALBERGIA SAXATILIS HOOK. F (FABACEAE) IN RATS AND MICE
ABSTRACT
The decoction of the leaves of Dalbegia saxatilis is used in Traditional Medicine for various ailments such as cough, small pox, skin lesions, bronchial ailments and toothache. The study was aimed at establishing a safety profile, evaluating phytochemical constituents and some...
28. EFFECTS OF DETOXIFICATION ON SOME PHARMACOLOGICAL PROPERTIES OF JATROPHA CURCAS LINN. (EUPHORBIACEAE) SEED OIL IN LABORATORY ANIMALS
Abstract
Jatropha curcas seed oil is a known energy source in biodiesel which but for its toxicity, also has potential of being used as food and in the pharmaceutical / cosmetic industries. This study was designed to detoxify solvent and mechanically extracted J. curcas oils and to asce...
29. MEDICINAL PLANTS USED IN THE MANAGEMENT OF DEPRESSIVE ILLNESSES: ANTIDEPRESSANT ACTIVITY OF METHANOL STEM BARK EXTRACT OF ADANSONIA DIGITATA L. IN MICE
ABSTRACT
Depression is a heterogeneous mood disorder that has been treated with a number of synthetic drugs. These drugs have adverse effects and delayed onset of action that compromise their therapeutic benefits. This makes it worthwhile to search for new antidepressant agents with pro...
30. PHARMACOLOGICAL AND TOXICOLOGICAL STUDIES OF THE METHANOL EXTRACT OF ACACIA ATAXACANTHA LEAF D.C. (LEGUMINOSAE) IN MICE AND RATS
ABSTRACT
Acacia ataxacantha is used in traditional medicine for management of pain and inflammation. Literature survey revealed that the safety and efficacy of such uses have not been scientifically validated. The present study was designed to study the pharmacological and toxicological...
31. PHYTOCHEMICAL AND SOME PHARMACOLOGICAL STUDIES OF THE LEAF OF OCHNA RHIZOMATOSA (VAN TIEGH.) KEAY [OCHNACEAE]
ABSTRACT
The extract of the leaf of Ochna rhizomatosa (van Tiegh.) Keay [Ochnaceae], a plant used in the treatment of malaria in Northern Cameroun, was subjected to preliminary phytochemical screening. The result revealed the presence of carbohydrates, steroids, cardiac glycosides, terp...
32. PHYTOCHEMICAL AND ANTIVENOM EVALUATIONS OF METHANOL LEAF EXTRACT OF CLERODENDRUM CAPITATUM (WILLD) SCHUM. AND THONN. (VERBENACEAE)
ABSTRACT
Clerodendrum capitatum (Willd) Schumach and Thonn. is a common medicinal plant found mainly in the tropical and sub-tropical regions of the world where it is used in traditional medicine for the treatment of various conditions including erectile dysfunction, wounds, diabetes me...
33. PHYTOCHEMICAL SCREENING AND ANTICONVULSANT STUDIES OF ETHYL ACETATE FRACTION OF ETHANOLIC EXTRACT OF THE LEAVES OF GLOBIMETULA BRAUNII (LORANTHACEAE) PARASITING ON PILIOSTIGMA THONINGII (FABACEAE)
ABSTRACT
The ethyl acetate soluble fraction of ethanol extract of leaves of Globimetula braunii, a plant used in ethnomedicine for the treatment of epilepsy and diabetes among other ailments, was subjected to phytochemical and anticonvulsant screening. The phytochemical techniques emplo...
34. SOME CARDIOVASCULAR ACTIVITIES OF THE AQUEOUS LEAF EXTRACT OF CROTON ZAMBESICUS LINN (EUPHORBIACEAE) IN LABORATORY ANIMALS
Abstract
Croton zambesicus Linn (Euphorbiaceae) is a highly valued medicinal plant in Nigeria and West African sub-region. It is used by traditional medicine practitioners in the treatment of various ailments including hypertension. This study aims to determine some cardiovascular activ...
35. SOME NEUROPHARMACOLOGICAL STUDIES ON ETHANOL EXTRACT AND FRACTIONS OF TAPINANTHUS GLOBIFERUS A. RICH MISTLETOE ON VITELLARIA PARADOXA HOST IN LABORATORY ANIMALS
ABSTRACT
Tapinanthus globiferus is a semi-parasite mistletoe which grows on branches of large number of trees including Vitellaria paradoxa. It used locally in the management of insomnia, epilepsy, anxiety, headaches and hypertension. This study evaluated the toxicity and neuropharmacol...
36. SOME PHARMACOLOGICAL PROPERTIES OF METHANOL EXTRACT OF ANISOPUS MANNII N.E.Br (ASCLEPIADACEAE) IN ALLOXAN-INDUCED HYPERGLYCAEMIC WISTAR RATS
ABSTRACT
Diabetes mellitus is a metabolic disorder that affects carbohydrates, lipids and proteins resulting in sustained hyperglycaemia which could lead to serious organ(s) damage and death. The aim of this study was to investigate some of the pharmacological properties of the methanol...
37. TOXICITY STUDIES OF THE ETHANOLIC STEM BARK EXTRACT OF RANDIA NILOTICA STAPF. IN RATS
ABSTRACT
The use of medicinal plant extracts to maintain health, prevent or cure various diseases is known since ancient times. However, most times, there is little or no knowledge of the associated possible toxic injuries on vital organs morphology or functions from the use of such pla...
38. EFFECT OF RANITIDINE ON PHARMACOKINETIC PARAMETERS OF METRONIDAZOLE IN HEALTHY HUMAN VOLUNTEERS
ABSTRACT
Pharmacokinetics is the study of the time course of drug movement in the body during absorption, distribution, metabolism and elimination.Drug interactions are pharmacodynamic, pharmacokinetic, or clinical responses to the administration of a drugcombination that differs from t...
39. PHARMACOGNOSTIC AND SOME BIOLOGICAL STUDIES ON MAYTENUS SENEGALENSIS (LAM.) EXELL (CELASTRACEAE)
ABSTRACT
Maytenus senegalensis (Celastraceae) is commonly known as thorny staff tree or confettii tree, is of high traditional use among the „Hausa‟ community of Northern Nigeria. Hence the present investigation was to establish the pharmacognostic parameters for the leaves and st...
40. SOME NEUROPHARMACOLOGICAL STUDIES OF EXTRACT AND FRACTIONS OF CRINUM ZEYLANICUM(L.) (AMARYLLIDACEAE)BULB IN LABORATORY ANIMALS
ABSTRACT
Crinum zeylanicum is a medicinal plant used in folk medicine for management of general debility, infantile seizures and pain. Some neuropharmacological effects of methanolic bulb extract of Crinum zeylanicum were studied in laboratory animals.The Phytochemical screening of the...
41. EVALUATION OF LEAF BASE EXTRACT OF SORGHUM BICOLOR (FAMILY: GRAMINEAE; POACEAE) FOR HAEMATOLOGICAL, IMMUNOMODULATORY AND OTHER PHARMACOLOGICAL ACTIVITIES
ABSTRACT
Sorghum bicolor is an annual plant having its different parts widely used ethnomedicinally for different ailments, which includes blood stimulation and body defence. A number of clinical conditions like cancer, surgery, certain drugs, HIV/AIDS and various stressors affect diffe...
42. PHARMACOLOGICAL EVALUATION OF THREE LOCALLY USED MEDICINAL PLANTS AGAINST CARBON TETRACHLORIDE-INDUCED HEPATOTOXICITY IN RATS
ABSTRACT
Drugs from plant and animal sources are increasingly becoming important in the therapeutic management of liver diseases. This study was undertaken to evaluate the prophylactic and curative effects of methanolic extracts of Balanites aegyptiaca root, Boswellia dalzielii stem bar...
43. PHARMACOLOGICAL RATIONALE FOR THE USE OF SOME MEDICINAL PLANTS AS ANTIEPILEPTIC AGENTS IN NIGERIA
ABSTRACT
The effects of the hydro-alcoholic root bark extracts of C. edulis and B. aegyptiaca were studied on pentylenetetrazole (PTZ) and Maximal electroshock (MES)-induced seizures in animal models. The effects of Flumazenil and Naloxone were studied on the anticonvulsant activity of...
44. PHYTOCHEMICAL AND PHARMACOLOGICAL STUDIES ON THE LEAF EXTRACT OF STEREOSPERMUM KUNTHIANUM (BIGNONIACEAE)
ABSTRACT
Stereospermum kunthianum (Bignoniacea) herb is used in Hausa ethnomedicine in treating bronchitis, veneral diseases, diarrheoa and dysentery. It is also used in the treatment of ulcers, leprosy, skin eruptions, respiratory ailments and gastritis. The plant is common in Northern...
45. SOME NEUROPHARMACOLOGICAL PROPERTIES OF METHANOLIC STEM BARK EXTRACT OF FICUS INGENS (MIQUEL) MIQUEL IN MICE AND CHICKS
ABSTRACT
Ficus ingens (Miquel) Miquel belongs to the Moraceae family. In some African countries, extracts of the bark are administered to cows with a low milk production, and to people suffering from anaemia, piles and diarrhea. The behavior of living organisms is a visible manifestatio...
46. ETHNOPHARMACOLOGICAL AND PHYTOCHEMICAL PROPERTIES OF SOME PLANTS USED IN THE MANAGEMENT OF PAIN
ABSTRACT
Pain is a worldwide problem and is associated with most disease conditions. The properties of herbs used to treat pain were investigated with the aim of confirming their use and finding out some pharmacological properties that may augment their analgesic activity. A total of ei...
47. PHARMACOLOGICAL EFFECTS OF METHANOLIC EXTRACT OF GARCINIA KOLA (HECKEL) SEED ON THE REPRODUCTIVE PROFILES OF SOME MALE EXPERIMENTAL ANIMALS
ABSTRACT
Garcinia kola is commonly consumed in Nigeria in social ceremonies and for leisure purposes. It is speculated to enhance sexual performance in males. The effects of methanolic extract of Garcinia kola seed on the male reproductive profiles of rats were determined at oral doses...
48. AN EVALUATION OF PUBLIC AWARENESS ON OMICRON VARIANT AMONG NIGERIAN CITIZENS (CASE STUDY OF LAGOS STATE)
BACKGROUND OF THE STUDY
The coronavirus disease 2019 (covid-19), which was discovered in Wuhan, China, in December 2019, has spread fast to practically every corner of the world Lorfa (2020). The condition is caused by the severe acute respiratory...
49. ISOLATION AND CHARACTERASATION OF ANTIMICROBIAL PRODUCING BACTERIA ASSOCIATED WITH THE SOIL
Background of study
Antibiotic resistance has recently emerged as a significant and alarming problem in the medical community. It is a result of the overuse or improper prescription of antibiotics, which has affected the empirical treatment of patients. Many pathogenic bacteria have dev...
